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By blocking the growth of abnormal blood vessels in the back of the eye, Avastin prevents leakage that could affect vision and cause vision loss

Explored as a possible aid for recovery and lean-mass preservation in frail or catabolic populations, though a Merck-sponsored Phase 2b trial in elderly hip-fracture patients (Adunsky et al., 2011, Archives of Gerontology and Geriatrics, PMID 21067829) was halted early over a cardiac safety signal rather than demonstrating a clear functional benefit

Unlike the brand-name medications (Mounjaro and Zepbound), compounded versions are not covered by insurance

10.1038/s12276-019-0216-4 45 HeW.CikM.Van PuyveldeL.Van DunJ.AppendinoG.LesageA.et al (2002)

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