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Effect of -aminobutyric acid-chitosan nanoparticles on glucose homeostasis in mice

[1] The compound is the (R)-enantiomer with one defined stereocenter, a calculated XLogP3-AA of 0.2, a topological polar surface area of 60.4 , and one hydrogen-bond donor and three hydrogen-bond acceptors

Kim BY, Cui ZG, Lee SR, et al

Vlamis-Gardikas, A., Potamitou, A., Zarivach, R., Hochman, A

L Volpicelli-Daley P Brundin 2018 Prion-like propagation of pathology in Parkinson disease Handb Clin Neurol 153 321 335 A Heintz-Buschart P Wilmes 2018 Human gut microbiome: function matters Trends Microbiol 26 7 563 574 MN Khan D Choudhary S Mehan Z Khan GD Gupta AS Narula 2025 Molecular mechanisms of GDNF/GFRA1/RET and PI3K/AKT/ERK signaling interplay in neuroprotection: therapeutic strategies for treating neurological disorders Neuropeptides 111 102516 C Pellegrini L Antonioli R Colucci C Blandizzi M Fornai 2018 Interplay among gut microbiota, intestinal mucosal barrier and enteric neuro-immune system: a common path to neurodegenerative diseases

The resulting aldehydic products including malondialdehyde and 4-hydroxynonenal form DNA adducts and stimulate compensatory colonocyte hyperproliferation, creating a cellular environment conducive to neoplastic transformation (16)