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Furthermore, increased apoptosis of LECs has been implicated in the development of diabetic cataracts in both human and animal models 66,67

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81,82 Aging also promotes the proinflammatory polarization of monocytes by increasing the plasma saturated fatty acid concentration, thereby increasing the production of IL-6 and TNF- but inhibiting the production of IL-10 and transforming growth factor- (TGF-1)