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Statistical analysis was done using Prism 7.0 (Graphpad software)

Within the same study, scRNA-seq revealed 49 upregulated and 211 downregulated genes in CALHM2 -KO cells

Fast-absorbing gel melts at body temperature

In line with previous observations in CLL cell lines, CB-839 did not cause significant apoptosis in the cells, and the level of double-negative events as determined using annexin V/PI staining remained stable in all the treatment groups (P = 0.93)