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Symptoms such as muscle tremors and abnormal movements have been observed, but these effects typically resolve with appropriate management and follow-up

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Metformin use and risk of B12 deficiency increases with the dose and the duration depletion can be seen as early as 3-4 months after starting so it is important to attend for follow up blood tests and talk to your doctor

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The mean deviation is also compared with the mean variability of the measurements of the gold standard